A patient with sickle cell disease admitted with acute splenic sequestration has ketorolac (Toradol) and morphine ordered intravenously for pain management. Which of the following principles should the nurse be aware of when administering ketorolac?
1) Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that can increase the risk of bleeding
2) Ketorolac should be administered with food to minimize gastrointestinal side effects
3) Ketorolac is contraindicated in patients with a history of asthma or allergic reactions to aspirin or other NSAIDs
4) Ketorolac can be safely administered to patients with renal impairment
5) Ketorolac is a long-acting opioid analgesic